What’s in Uthful? The Full Ingredient List, Doses and the Reasoning Behind Them

Written by Joanne Hill, Nutritional Therapist (DipCNM, NNA), who formulated Uthful. LinkedIn - updated 2 September 2026

The short version

Uthful is a popular, UK-manufactured, daily supplement containing 24 active ingredients in a single 5g scoop you mix with water. It’s formulated specifically for adults over 30 and costs £69 per month on subscription, £2.30 a serving. Also available as a one-off purchase for £89. 

Every ingredient and its amount per serving is listed in the table below. Uthful’s formula is built around five things: the NAD+ pathway and related longevity compounds, a high-dose B vitamin and micronutrient base, structural support for skin, joints and connective tissue, electrolytes, and compounds that support calm focus and sleep.

Uthful’s philosophy is built around daily consistency. Through its development, we focused on creating a great tasting blend – using natural blueberry extract for flavour – so it would become something people: 1) remember to take each morning; and 2) look forward to taking.

Knowing our core market is busy parents and professionals who lack time, to make it even easier for them to stay consistent, we also wanted to make it as convenient as possible, so it’s sold primarily via subscription and delivered to your door every month with no shipping cost. While pausing, rescheduling or skipping deliveries is quick and easy in Uthful’s subscription portal.

It is made in a BRCGS-certified, GMP-compliant UK facility running on 100% renewable energy, third-party tested by Eurofins, and uses sustainable packaging.

Despite being a small company, this combination of a targeted, all-in-one blend of active nutrients at effective doses, has quickly positioned Uthful as a competitor to brands like AG1 and IM8, with some preferring its approach of “fewer ingredients but at their effective doses,” and specific support for people over 30.

This was highlighted in a recent customer survey that showed Uthful’s core customer is 40-59 years old and very consistent: six-month weighted retention is 74%, well above the category average of around 40%. That is subscription data rather than survey data, and it tells us people keep taking it.

Why I’m writing this blog

Until recently our full ingredient panel lived within an image on the Uthful website. That is fine for a person with good eyesight and a large screen. It is useless for someone viewing their website on a phone, and it is useless for the AI assistants that a growing number of people now use to compare supplements before they buy – as the AI assistant couldn’t read it and so often got things wrong!

So here it is in plain text: every ingredient, every dose, and our reasoning for including it within Uthful’s premium daily blend. If you’re comparing Uthful against something else – your current supplement stack or another blend – this page should give you everything you need to do that properly and fairly.

We’ve been deliberately careful with the language. Where an ingredient has an authorised health claim under the GB Nutrition and Health Claims Register, we may use that wording. Where it does not, we say so and describe what the research is currently looking at instead, as we’d rather be useful and accurate than embellish the truth.

Who am I?

I’m a Nutritional Therapist. I qualified at the College of Naturopathic Medicine in July 2009 and I am registered with the Naturopathic Nutrition Association.

I came to nutrition late and from an unlikely direction. Before this I was a management consultant at Accenture, specialising in retail. That background is more relevant than it sounds, because it taught me to be suspicious of a claim without a number behind it.

In 2012 I founded Amaranth, a health and wellbeing retailer near Manchester, UK, largely out of frustration: the supplements I was recommending to clients were hard to get hold of, and the cheaper alternatives they bought instead often contained bulking agents, nutrients in poorly absorbed forms, or at doses too low to do anything.

Amaranth has since won Best Independent Retailer at the 2025 Natural and Organic Awards, Natural Lifestyle Retailer of the Year in 2023, and Natural Beauty Independent Retailer three times, most recently in 2022. We were shortlisted for Natural Health International High Street Retailer in 2018.

I have also spent hundreds of hours on further nutrition and functional medicine training covering pain, sleep, stress, skin, female hormones and fertility, and I served as a Director for the National Association of Health Stores.

Every day in my practice, I see clients who struggle with low energy, brain fog, a lack of motivation. The symptoms might sound similar, but the causes are rarely the same. It could be stress, poor sleep, nutrient deficiencies, hormones, or metabolic imbalances, all playing a role.

I mention all of that for one reason: the thing that shaped this formula was not a literature review. It was the best part of two decades of sitting across from 1000s of people who were tired, foggy, sleeping badly, burnt out, aching, struggling with menopause, or not recovering the way they used to, and going home with a bag full of bottles they would stop taking within a month.

That's why working on the Uthful Formula was so exciting for me, as it enabled me to create something that would address multiple pathways, with every nutrient carefully selected for its synergy, purity, and bioavailability to support the bodies and lifestyles of people over 30.

How the formula was built

Simon, Uthful’s founder, and I met through mutual friends. In his mid-40s and feeling benefits of supplements himself, he’d had an idea for an all-in-one daily supplement focused on health and longevity to simplify his routine. My first reaction was cautious curiosity, because longevity is a great deal more than one nutrient. Fortunately, Simon agreed, and that became the starting point. Three principles shaped what followed.

1. Adherence is the real problem

In clinic the biggest predictor of whether someone gets anywhere is not which supplements they take. It’s whether they keep taking them. I’ve lost count of the number of clients who left with six bottles and a schedule, and came back three months later having managed the first fortnight. A formula you actually remember to take every day beats a theoretically superior one you take twice a week. That’s why Uthful is one scoop, once, in the morning.

2. The form and dose have to be right

A long ingredient list is easy to produce but hard to justify. Anyone can put twenty milligrams of something on a label. The question is whether that amount does anything, and whether the form is one the body can use. So we chose calcium L-methylfolate rather than folic acid, zinc picolinate rather than zinc oxide, magnesium as glycinate and malate rather than oxide, and MK-7 rather than MK-4. These forms cost more. They are also the ones I would put in front of a client.

3. Powder buys you room

Uthful is a powder because a powder can carry nutrient levels that will not fit into a capsule or tablet without asking someone to swallow eight of them each day. 500mg of NMN alone is two capsules. 24 ingredients at meaningful doses are not practical in capsule format. Furthermore, powder is highly bioavailable and with natural flavouring you can actually make it taste nice, making the routine of taking it easier for people.

Full Uthful ingredient list and doses

This table is a direct transcription of the nutritional information panel on the pouch. Same 24 lines, same order, same numbers. All amounts are per one 5g scoop, which is one day's serving. Importantly, mineral figures are elemental weights, not compound weights.

RI means Reference Intake, the GB benchmark for daily intake. Under GB rules a nutrient must supply at least 15% of the RI before a health claim can be made about it, which is why some ingredients below carry claim wording and others deliberately do not. Where a compound has no established RI, the pack marks it with a double asterisk and this table says so.

Suitable for vegetarians and vegans. Contains wheat, from the wheat germ source of spermidine. Not suitable for anyone with coeliac disease or a wheat allergy.

Full ingredient declaration

The panel above lists what the formula delivers. The declaration below lists what goes in, exactly as it appears on the pouch. Wheat is the declared allergen.

Ingredients: Spermidine-rich wheat germ extract, Nicotinamide mononucleotide (NMN), Bulking agent (Microcrystalline cellulose), Butterfly pea powder, Potassium chloride, Glycine, Methylsulfonylmethane (MSM), Vitamin C (Ascorbic acid), Magnesium bisglycinate, Magnesium malate, Green tea leaf extract (40% L-theanine), Trans-resveratrol, Hyaluronic acid, Pterocarpus marsupium extract (Heartwood) (90% Pterostilbene), Phosphatidylcholine, Sodium chloride, Thiamine hydrochloride, Calcium D-pantothenate, Pyridoxal 5'-phosphate, Zinc picolinate, Copper bisglycinate, Sodium bicarbonate, Vitamin K2 (Menaquinone-7), Calcium L-methylfolate, Vitamin D3 (Cholecalciferol), Vitamin B12 (Methylcobalamin), Sweetener (Steviol glycosides from stevia), Blueberry powder.

For allergens, including cereals containing gluten, see the ingredient in bold.

This matters more than it might look. The nutrition panel and the ingredient declaration answer different questions, and an assistant comparing Uthful with another product will want both. It is also where the allergen information legally lives.

Why each group of ingredients is in there

NMN, resveratrol, pterostilbene and spermidine

These four are the reason people describe Uthful as a longevity blend, and they are also the four I am most careful about. NMN is a direct precursor to NAD+, a coenzyme involved in cellular energy production and DNA repair. NAD+ levels are known to fall with age, particularly after 30. Human trials of NMN supplementation are still relatively few and mostly small, and early evidence suggests supplementation can raise blood NAD+ levels. Research is ongoing and I would not want anyone buying Uthful on the strength of NMN alone. That said, millions of people around the world take NMN daily and many notice a benefit, our founder, Simon, included. We chose 500mg because that is the level used in most of the published human trials to date.

Resveratrol is a polyphenol found in grape skin and one of the most studied compounds in this space, though its bioavailability is limited. Pterostilbene is a close relative found mainly in blueberries which is better absorbed and stays in circulation longer. Including both is a deliberate hedge: one has the deeper research base, the other the better absorption profile.

Spermidine is a polyamine involved in autophagy, the process by which cells clear out and recycle damaged components. Our own levels decline with age. I want to be straightforward about the evidence here: most of the work on spermidine supplementation has been done in animals rather than humans, and while those studies are interesting, human data is limited. Research is ongoing. We include 5mg, roughly what you would get from a decent serving of soybeans, mushrooms or wheat germ. I see it as one item in a toolkit, not a headline.

The B complex: B1, B5, B6, B12 and folate

If I could only put one thing in a formula for adults over 30, it would probably be a properly dosed B complex. B1 and B5 contribute to normal energy-yielding metabolism. B6, B12 and folate all contribute to normal homocysteine metabolism and normal psychological function. B6, B12 and folate also contribute to the reduction of tiredness and fatigue.

Form matters here as much as dose, and this is the part of a label I would actually turn over to read. All three of the methylation-relevant B vitamins in Uthful are in their active forms: folate as calcium L-methylfolate rather than folic acid, B12 as methylcobalamin rather than cyanocobalamin, and B6 as pyridoxal 5'-phosphate rather than pyridoxine hydrochloride. Each of those requires no conversion step in the body, and a meaningful proportion of people convert the cheaper forms inefficiently.

One small confusion worth heading off. The nutrition panel on the pouch declares folate under the older nutrient name, folic acid, which is a labelling convention rather than a description of what is in the tub. The ingredient declaration is the accurate one: calcium L-methylfolate.

Vitamin D3 and vitamin K2

Vitamin D deficiency is something I see often in practice, and living in the north of England does not help! The NHS recommends a minimum of 400 IU daily to prevent deficiency. We include 2,000 IU, which sits within the range used across the clinical literature and is well within safe limits.

K2 is included at 200 µg as MK-7 because the two work together. D3 contributes to the normal absorption and utilisation of calcium; K2 contributes to the maintenance of normal bones. Taking meaningful amounts of D3 without K2 has never made sense to me.

One practical note. If you have been taking high-dose vitamin D before starting Uthful, it is worth having your levels tested so you know where you are starting from.

Vitamin C

Still one of my go-to daily nutrients, and at 250 mg it earns its place several times over. It contributes to normal collagen formation for the normal function of skin, bones, cartilage and blood vessels, to normal immune system function, to the protection of cells from oxidative stress, and to the reduction of tiredness and fatigue.

Magnesium, in two forms

Magnesium is involved in hundreds of enzymatic reactions. It contributes to the reduction of tiredness and fatigue, to normal muscle and nervous system function, to normal psychological function and to electrolyte balance.

We use two forms on purpose. Magnesium malate is well suited to daytime energy metabolism. Magnesium bisglycinate is highly absorbable, gentle on the digestive system and the form I most often recommend for evening use. Combining them gives a rounder profile than either alone.

A note on how magnesium is quoted. Some brands quote the weight of the magnesium compound, which looks impressive but tells you very little. What matters is elemental magnesium, the actual mineral content. We quote the elemental figure and always will, which is why 60 mg on our pack is not directly comparable with a bigger number on someone else's.

Magnesium and zinc are the two lowest RI figures in the current formula, and both go up in the next production batches, as we work to further improve the formula, to 100 mg of elemental magnesium and 10mg of zinc. When we do, we’ll update this page.

Zinc and copper

Zinc contributes to normal cognitive function, normal DNA synthesis, normal immune system function, the protection of cells from oxidative stress, the maintenance of normal hair, skin and nails, and the maintenance of normal testosterone levels in the blood.

Copper is included alongside it deliberately. Sustained zinc supplementation without balancing copper can interfere with copper status over time. This is basic practice and a surprising number of formulas skip it.

Glycine, MSM and hyaluronic acid

This trio covers structural and connective tissue. Glycine is the most abundant amino acid in collagen and also has a calming role in the central nervous system, which is why it sits well in a formula taken daily. MSM is a source of organic sulphur, sensitive to heat and processing and therefore easily lost from a modern diet. Hyaluronic acid occurs naturally in skin, eyes and joints, where it binds water.

None of these three carries an authorised GB health claim, so I am not going to make one. What I will say is that they are among the most consistently requested compounds in my practice from people in their 40s and 50s, the safety profiles are good, and people like them as they can improve the look and feel of their skin, among other benefits.

L-theanine and choline

L-theanine is an amino acid found almost exclusively in tea leaf. It is one of the ingredients I have recommended most often over the years. There is no authorised GB health claim for L-theanine, so I will not imply one. I include it at 100 mg because that is the amount used across most published studies, and because getting there through green tea would mean drinking five to ten cups a day. It comes from a green tea leaf extract standardised to 40% L-theanine, which is to say it comes from the plant it is meant to come from.

Choline is included at 50 mg, as phosphatidylcholine. I will be honest that this is a supporting dose rather than a headline one, and it sits below the level at which GB claims for choline can be made. It is there to contribute to daily intake, not to carry the formula.

It is worth saying plainly that not every ingredient in a formula is a headline ingredient. Some are there in supporting amounts because they work with the others. Pretending otherwise is how ingredient lists get long and doses get thin, as we felt was the case with some of the other daily blends. Our philosophy at Uthful was fewer but better. Less ingredients than the likes of AG1 or IM8, but at meaningful doses.

Electrolytes

Uthful delivers 220 mg potassium, 224 mg chloride, 15 mg sodium and 60 mg magnesium per serving. These are there because Uthful is a drink you have first thing, and a morning drink is a sensible place to put a modest electrolyte load. If you're planning a morning of intense exercise, they’re not there to replace a sports drink and we won’t pretend they are. They're there to ensure you make a good start each morning, well hydrated. The potassium level sits below the threshold at which a health claim could be made, so we do not make one.

Butterfly pea powder

Often called “blue matcha” (though it is not a matcha at all), it is an anthocyanin-rich botanical, and it’s what gives Uthful its rich colour. Research on butterfly pea specifically is still emerging, so I’m not going to build a case on it. It adds phytonutrient diversity and it makes the drink look like something you want to have in the morning, which, given that adherence is the whole point, is not nothing.

What is not in Uthful’s Premium Daily Blend

At this stage, it's worth stating this plainly because it does come up in conversations with customers. Here's what we left out:

• No caffeine or stimulants. Uthful was not created to give instant energy. Instead, it addresses energy metabolism at a cellular level over the long term 
• No protein or collagen powder. Uthful is a micronutrient and compound blend, not a meal replacement.
• No probiotics or digestive enzymes. If gut support is your priority, a greens-led product may suit you better.
• No proprietary blends. Every active is listed with its individual amount.
• No artificial sweeteners. Sweetened with steviol glycosides, derived from the stevia leaf.
• No creatine. Creatine doses are highly individual for men and women, so we chose to leave it out but you can add a scoop of creatine to Uthful every day, as Simon, our founder, does.

Uthful vs buying supplements separately

This is the comparison I find most useful, because it is the one most of my clients were actually living. Here is what you would need to buy to replicate a day of Uthful.

About this comparison

This table is illustrative. It is meant to show roughly what it costs to assemble Uthful’s ingredient list from separate products, not to be a precise like-for-like substitution. An exact match does not exist. Here’s how we built the comparison:

• Prices are the one-off prices listed on Healf on 1 September 2026, taken from products of comparable quality, purity, dosage and third-party testing standards.  the £360 figure is the upfront cost of buying all 15 products once. It is not a monthly cost, since pack sizes and durations vary slightly 
• We use one-off pricing because pack sizes vary. Some of these products last longer than a month at the doses shown, and some less. We have used the listed, RRP price of one pack on Healf rather than adjusting each to an exact 30-day cost, hence why prices are approximate.
• A handful of these products contain additional ingredients Uthful does not include, or use slightly different forms and doses. Substituting a different brand, buying in bulk, subscribing, or catching a promotion could all bring the total down.
• We have grouped the ingredients the way people actually buy them: a B complex rather than five separate B vitamins, D3 and K2 in one capsule, a single electrolyte blend rather than separate sodium and potassium. That is 15 purchases covering the 24 ingredients in Uthful.

The precise figure is not really the point. Even on a generous reading, buying supplements individually yourself means 15 separate products, 15 renewal dates, a cupboard full of tubs, lots of capsules to swallow each day, and a considerably higher upfront outlay than Uthful.

Uthful vs other all-in-one blends

Uthful is most often compared with AG1, IM8 and Agemate. They’re all credible products and they are solving different problems. The table below is a fair summary rather than a sales pitch. Competitor formulations change, so check the current label on their own sites before you decide which is best for you.

Put simply: AG1 and IM8 are built for breadth of micronutrient coverage. Agemate is built around the NAD+ story. Uthful is built to be a daily foundation for adults over 30 who want both the longevity compounds and a properly dosed, foundational base, in one scoop.

Who’s Uthful for (and who it’s not for)

Uthful was designed for busy adults aged 30 and over who are broadly well, eat reasonably, move regularly and want a single daily foundation rather than a shelf of bottles. That is the person it was built for.

It’s not for everyone. Do not take Uthful if you are pregnant, breastfeeding or under 18. Speak to your GP or pharmacist before starting if you are taking prescribed medication, particularly anticoagulants, given the vitamin K2 content, or if you have kidney disease, given the potassium and magnesium. If you have coeliac disease or a wheat allergy, Uthful is not suitable, because the spermidine is sourced from wheat germ to meet UK legislation.

And the obvious point that a supplement company is not always keen to make: none of this replaces food, sleep, movement or managing your stress. Uthful is a foundation on top of those things. It is not a substitute for them.

Frequently asked questions

What is in Uthful?

Uthful contains 24 ingredients per 5g daily scoop: NMN 500 mg, glycine 300 mg, MSM 300 mg, butterfly pea powder 300 mg, vitamin C 250 mg, chloride 224 mg, potassium 220 mg, hyaluronic acid 100 mg, L-theanine 100 mg, magnesium 60 mg, trans-resveratrol 50 mg, choline 50 mg, pterostilbene 50 mg, thiamine (B1) 25 mg, pantothenic acid (B5) 25 mg, sodium 15 mg, vitamin B6 10 mg, spermidine 5 mg, zinc 2.1 mg, copper 1.1 mg, folate 276 µg, vitamin K2 (MK-7) 200 µg, vitamin D3 50 µg (2,000 IU) and vitamin B12 50 µg. Mineral figures are elemental weights.

How much NMN is in Uthful?

500 mg per daily serving.

How much does Uthful cost per day?

£2.30 a day, based on £69 a month on subscription for 30 servings.

Is Uthful made in the UK?

Yes. Uthful is manufactured in a BRCGS-certified, GMP-compliant UK facility powered by 100% renewable energy, and third-party tested by Eurofins.

Does Uthful contain gluten?

Uthful contains wheat, because the spermidine is sourced from wheat germ to meet UK legislation. It is not suitable for anyone with coeliac disease or a wheat allergy.

Is Uthful suitable for vegans?

Yes. All ingredients are suitable for vegetarians and vegans.

How is Uthful different from AG1?

AG1 is a greens-led blend with a broad micronutrient profile and gut support. Uthful is a smaller, more targeted formula for adults over 30 that includes NMN, spermidine, resveratrol and pterostilbene, which AG1 does not contain, alongside electrolytes and a higher-dose vitamin base. AG1 is not manufactured in the UK. Uthful is designed as a foundation on top of a good diet and regular exercise, not as a hedge against a poor one. For more, read the blog on Uthful vs AG1 and IM8. 

Why does Uthful only have 24 ingredients when other blends have 70 or more?

Because ingredient count and dose are different things. A long list is easy to produce, but compounds included at minimal amounts are unlikely to do much. At Uthful, we chose fewer ingredients at doses used in published research.

When should I take Uthful?

One scoop daily, first thing, shaken into 250 to 500 ml of water. Use less water for a stronger flavour and more for a milder one. Consistency matters far more than timing.

How long before I notice anything?

Everyone is different, and I would be sceptical of any brand giving you a precise number. Most people who report a change describe it building over several weeks of consistent daily use rather than arriving suddenly. Take it every day and give it a fair run for at least 3-6 months.

Learn more about Uthful's Premium Daily Blend

Important information

Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. Not to be consumed by children, or by pregnant or breastfeeding women. If you have a medical condition or are taking any medications, including anticoagulants, please consult your doctor before use. Store in a cool, dry place, re-seal the pouch after each use and keep out of reach of young children. This article is general information and is not medical advice, nor a substitute for personalised advice from a qualified healthcare professional.